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Revolutionary Anti-Aging
Skincare System of Products

Beautiful Skin Without Harsh Chemicals

Did you know your skin has a microbiome, and it plays a crucial role in skin aging, discoloration, and even acne? That’s why it’s important to avoid beauty products that contain harsh chemicals, as these may negatively disrupt the microbiome. Instead, choose products that fortify and balance the skin microbiome for healthy, balanced, and youthful-looking skin!



OR, Join Plexus now for just an annual fee of just $9.99, and you'll get ALL Plexus products at wholesale cost ALL YEAR! You'll even get your own link to share with your family and friends -- so you can earn cashback too!

The Plexus Joyōme Series

The Plexus Joyōme product line offers a cleanser, day serum, and overnight repair that specifically targets the skin microbiome to protect against harmful pathogens, balance the skin’s pH, prevent excessive water loss, produce essential nutrients, and promote collagen production to improve skin elasticity and reduce the appearance of fine lines and wrinkles.


Joyōme Revitalizing Daily Cleanser

Radiate confidence with refreshingly clean skin. Joyome® Revitalizing Daily Cleanser gently washes away dirt, oil and makeup, leaving your skin feeling soft, smooth and hydrated. This revitalizing formula is infused with cranberry extract to gently exfoliate, while natural prebiotics reduce moisture loss and is pH formulated to support a balanced and healthy skin microbiome.

Joyōme® Illuminating Day Serum

Joyōme Illuminating Day Serum helps visibly rewind the signs of aging with six clinically demonstrated anti-aging key ingredients. Packed with premium, designer peptides, Joyōme dramatically reduces the look of unwanted wrinkles formed by facial expressions including crow’s feet, forehead lines, and smile lines. It also reduces the appearance of oversized pores, dark circles and under eye puffiness while plumping and hydrating your skin to leave it looking brighter and beautifully luminous all day long. Available in a one-month supply or a two-month supply.


Joyōme® Intensive Overnight Repair

Joyōme Intensive Overnight Repair is a powerful, ultra-hydrating serum that delivers multiple anti-aging benefits. Designed to enhance the absorption of five key ingredients, skin feels firmer and smoother, lines and wrinkles visibly reduced, and the appearance of age spots and redness is diminished. Our patent-pending Microbiome Balancing Complex also replenishes your skin’s moisture barrier to defend against environmental age accelerators. Available in a one-month supply or a two-month supply.

Joyōme™ Multi-Action Collagen Complex

This powerful, multi-action formula features a unique beauty blend of highly-bioavailable Types I and III Collagen, Ceramides, Biotin, prebiotics, and antioxidant-rich superfoods, which combine to address the signs of aging in three key ways. This advanced formula supports your skin structure with the collagen it needs, boosts your body’s ability to make more collagen naturally, and reduces collagen breakdown. Available in a 30-day cannister or stick packs.

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Glow+ Illuminating Elixir

Bring new life to your skin with this convenient beauty essential. Glow+ Illuminating Elixir works from within to help brighten, firm, and even out your complexion while boosting your skin’s collagen density for a healthy, youthful glow.


With one packet daily, you can reduce fine lines and wrinkles, improve skin elasticity, and enjoy the benefits of powerful antioxidants.*

  • Increases skin brightness, nourishing thirsty skin from within with essential hydration that delivers a radiant glow**

    • Helps build collagen density to support skin, allowing it to maintain its bounce, elasticity, and smooth texture*

  • Provides powerful antioxidants to protect against visible skin damage and accelerated aging effects caused by environmental stressors*

  • Pairs perfectly with Joyōme® Multi-Action Collagen Complex

Healthy Skin from the Inside Out

Healthy skin is not just about topical creams and washes. Healthy, glowing, youthful-looking skin starts on the inside with the vitamins and nutrients your body needs to develop healthy skin. Here are some of our most popular “inside out” skincare products.

Six Reasons to Target Your Skin Microbiome in Your Skincare Routine



The skin microbiome acts as a protective barrier against harmful bacteria, viruses, and fungi. It helps prevent the growth of pathogenic organisms that can cause infections, breakouts, and other skin problems.


Moisture Regulation

The skin microbiome aids in maintaining optimal moisture levels on the skin's surface. It helps prevent excessive water loss, keeping the skin hydrated and supple. Well-hydrated skin appears plump, youthful, and radiant.


Anti-Aging Effects

The skin microbiome can also impact the aging process of the skin. Certain beneficial bacteria produce peptides and other compounds that help promote collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles.


PH Balance

The skin's pH balance is important for maintaining healthy and beautiful skin. The skin microbiome helps regulate the skin's pH levels, preventing it from becoming too acidic or alkaline. An imbalanced pH can lead to various skin issues like dryness, irritation, and acne.


Inflammation Control

A balanced and diverse skin microbiome helps regulate the skin's immune system in response and control inflammation. This is important for preventing and managing skin conditions like eczema, rosacea, and acne, which can affect the skin's appearance.


Nutrient Production

Some microorganisms in the skin microbiome produce essential nutrients, such as vitamins and fatty acids, that are beneficial for skin health and beauty. These nutrients can nourish the skin and enhance its overall appearance. It is important to note that maintaining a healthy skin microbiome requires a balanced skincare routine, a healthy diet, and avoiding harsh chemicals that may disrupt the microbiome.

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